First structure of key COVID enzyme at human body temperature

Aug 17 2022

Scientists used X rays to decipher three dimensional  structure.

To study the enzyme's structure, researchers used a technique called X-ray crystallography at Brookhaven Lab's National Synchrotron Light Source II (NSLS-II)

Exploring the enzyme at elevated humidity also mimics the physiological conditions within water-filled cells—and may provide additional clues to guide drug design.

Scientists told that for this project to work it was very important that the team worked  remotely, and which was done leading to the project's success. 

The results showed that some water molecules bind loosely than others. And also they bind in the high-humidity condition.

This study and all the related work is published in Scientific Reports in the nature section of journals.

Scientists were grateful for the synergy displayed by the entire team. Their team included scientists from Brookhaven lab and CUNY and some scientist were from Diamond light source from the UK.